Publications
Mahasa PS, Milambo MJP, Nkosi SF, Mukwada G, Nyaga MM, Tesfamichael SG. The Relationship Between Climate Change and Breast Cancer and Its Management and Preventative Implications in South Africa. Int J Environ Res Public Health. 2025 Sep 25;22(10):1486. doi: 10.3390/ijerph22101486. PMID: 41154889; PMCID: PMC12563603.
Mhango C, Ndovie W, Zuza A, Chinyama E, Kawonga F, Matambo E, Kumwenda B, Kamng’ona AW, Chaguza C, Nyaga MM, Donato CM, Jere KC. Complete genome sequence of a Kayfunavirus bacteriophage identified in Blantyre, Malawi. Microbiol Resour Announc. 2025 Nov 10:e0086725. doi: 10.1128/mra.00867-25. Epub ahead of print. PMID: 41211825.
Manjate F, Chirinda P, Mwangi P, João ED, Mogotsi M, Garrine M, Jr AM, Vubil D, Nobela N, Kotloff K, Nataro JP, Nhampossa T, Acácio S, Weldegebriel G, Tate JE, Parashar U, Mwenda JM, Alonso PL, Nyaga M, Cunha C, Mandomando I. Whole-genome analysis of rotavirus G1P[8] and other Wa-like strains in Mozambican children: evidence of genetic variations of pre-vaccine G1P[8] strains from Manhiça, Mozambique. Microb Genom. 2025 Oct;11(10):001522. doi: 10.1099/mgen.0.001522. PMID: 41150057; PMCID: PMC12562872.
Dor G, Wilkinson E, Martin DP, Moir M, Tshiabuila D, Kekana D, Ntozini B, Joseph R, Iranzadeh A, Nyaga MM, Goedhals D, Maponga T, Maritz J, Laguda-Akingba O, Ramphal Y, MacIntyre C, Chabuka L, Pillay S, Giandhari J, Baxter C, Hsiao NY, Preiser W, Bhiman JN, Davies MA, Venter M, Treurnicht FK, Wolter N, Williamson C, von Gottberg A, Lessells R, Tegally H, de Oliveira T. Tracing the spatial origins and spread of SARS-CoV-2 Omicron lineages in South Africa. Nat Commun. 2025 May 28;16(1):4937. doi: 10.1038/s41467-025-60081-0. PMID: 40436832; PMCID: PMC12120024.
Matambo E, Kawonga F, Mhango C, Chinyama E, Msowoya J, Majengo C, Maseko S, Shange N, Baloyi S, Mogotsi MT, Dennis FE, Donato C, Kumwenda B, Nyaga MM, Chaguza C, Jere KC. Draft genomes of norovirus from stool samples of under-five children presenting with gastroenteritis in Malawi from 2012 to 2024. Microbiol Resour Announc. 2025 Aug 14;14(8): e0060225. doi: 10.1128/mra.00602-25. Epub 2025 Jul 28. PMID: 40719297; PMCID: PMC12352048.
Agbla JM, Mogotsi MT, Zohoun AG, Shange ND, Capochichi A, Ogunbayo AE, Assogba R, Khakha S, Sossou A, Sondlane H, Mwenda JM, Esona MD, Nyaga MM. Unveiling a Shift in the Rotavirus Strains in Benin: Emergence of Reassortment Intergenogroup and Equine-like G3P [8] Strains in the Post-Vaccination Era. Viruses. 2025 Aug 7;17(8):1091. doi: 10.3390/v17081091. PMID: 40872805; PMCID: PMC12390709.
Shange ND, Mogotsi MT, Ogunbayo AE, Page N, Sondlane H, Esona MD, Kumwenda B, Mhango C, Kawonga F, Matambo E, Mingle SNK, Dennis FE, Khuzwayo JC, Makoah NA, Donato CM, Nyaga MM. Whole genome characterisation of DS-1-like G8P [4] rotavirus A strains circulating in South Africa between 2009 and 2021 reveals endemic sub-lineages and evidence of radical epitope changes. Infect Genet Evol. 2025 Oct; 134:105818. doi: 10.1016/j.meegid.2025.105818. Epub 2025 Sep 5. PMID: 40915595.
Mogotsi MT, Ogunbayo AE, O’Neill HG, Nyaga MM. High Detection Frequency of Vaccine-Associated Polioviruses and Non-Polio Enteroviruses in the Stools of Asymptomatic Infants from the Free State Province, South Africa. Microorganisms. 2024 Apr 30;12(5):920. doi: 10.3390/microorganisms12050920. PMID: 38792747; PMCID: PMC11124149.
Mogotsi MT, Ogunbayo AE, Bester PA, O’Neill HG, Nyaga MM. Longitudinal analysis of the enteric virome in paediatric subjects from the Free State Province, South Africa, reveals early gut colonisation and temporal dynamics. Virus Res. 2024 Aug; 346:199403. doi: 10.1016/j.virusres.2024.199403. Epub 2024 Jun 1. PMID: 38776984; PMCID: PMC11169482.
Mooko T, Bisiwe FB, Chikobvu P, Morobadi MD, Mofokeng TRP, Nyaga MM, Kemp G, Goedhals D, Ndlovu KCZ. The prevalence of HIV resistance mutations and their influence on the shedding of HIV-1 into peritoneal dialysis effluent. J Med Virol. 2024 Jun;96(6): e29734. doi: 10.1002/jmv.29734. PMID: 38884452.
T, Bisiwe FB, Chikobvu P, Morobadi MD, Mofokeng TRP, Nyaga MM, Kemp G, Goedhals D, Ndlovu KCZ. The prevalence of HIV resistance mutations and their influence on the shedding of HIV-1 into peritoneal dialysis effluent. J Med Virol. 2024 Jun;96(6): e29734. doi: 10.1002/jmv.29734. PMID: 38884452.
Nwokorogu VC, Pillai S, San JE, Pillay C, Nyaga MM, Sabiu S. A metagenomic investigation of the faecal RNA virome structure of asymptomatic chickens obtained from a commercial farm in Durban, KwaZulu-Natal province, South Africa. BMC Genomics. 2024 Jun 24;25(1):629. doi: 10.1186/s12864-024-10517-6. PMID: 38914944; PMCID: PMC11194887.
Sondlane H, Ogunbayo A, Donato C, Mogotsi M, Esona M, Hallbauer U, Bester P, Goedhals D, Nyaga M. Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa. Virus Res. 2024 Sep; 347:199421. doi: 10.1016/j.virusres.2024.199421. Epub 2024 Jul 5. Erratum in: Virus Res. 2024 Nov; 349:199449. doi: 10.1016/j.virusres.2024.199449. PMID: 38942296; PMCID: PMC11283024.
Mooko T, Bisiwe FB, Mondleki E, Morobadi MD, Chikobvu P, Nyaga MM, Bala A, Goedhals D, Mofokeng TRP, Kemp G, Ndlovu KCZ. Steady-state pharmacokinetics of lamivudine in end-stage kidney failure persons with detectable and undetectable HIV-1 RNA in peritoneal dialysis effluent. Eur J Med Res. 2024 Jul 18;29(1):374. doi: 10.1186/s40001-024-01972-8. PMID: 39026368; PMCID: PMC11256402.
Chaguza C, Chibwe I, Chaima D, Musicha P, Ndeketa L, Kasambara W, Mhango C, Mseka UL, Bitilinyu-Bangoh J, Mvula B, Kipandula W, Bonongwe P, Munthali RJ, Ngwira S, Mwendera CA, Kalizang’oma A, Jambo KC, Kambalame D, Kamng’ona AW, Steele AD, Chauma-Mwale A, Hungerford D, Kagoli M, Nyaga MM, Dube Q, French N, Msefula CL, Cunliffe NA, Jere KC. Genomic insights into the 2022-2023Vibrio cholerae outbreak in Malawi. Nat Commun. 2024 Jul 26;15(1):6291. doi: 10.1038/s41467 024-50484-w. PMID: 39060226. 3. 4. 5. 6. 7. 8. 9.
Manjate F, João ED, Mwangi P, Chirinda P, Mogotsi M, Garrine M, Messa A Jr, Vubil D, Nobela N, Kotloff K, Nataro JP, Nhampossa T, Acácio S, Weldegebriel G, Tate JE, Parashar U, Mwenda JM, Alonso PL, Cunha C, Nyaga M, Mandomando I. Genomic analysis of DS-1-like human rotavirus A strains uncovers genetic relatedness of NSP4 gene with animal strains in Manhiça District, Southern Mozambique. Sci Rep. 2024 Dec 28;14(1):30705. doi: 10.1038/s41598-024-79767-4. PMID: 39730435; PMCID: PMC11680989.
Mwangi PN, Potgieter RL, Uwimana J, Mutesa L, Muganga N, Murenzi D, Tusiyenge L, Mwenda JM, Mogotsi MT, Rakau K, Esona MD, Steele AD, Seheri ML, Nyaga MM. The Evolution of Post-Vaccine G8P [4] Group a Rotavirus Strains in Rwanda; Notable Variance at the Neutralization Epitope Sites. Pathogens. 2023 Apr 28;12(5):658. doi: 10.3390/pathogens12050658. PMID: 37242329; PMCID: PMC10223037.
Ogunbayo AE, Mogotsi MT, Sondlane H, Sabiu S, Nyaga MM. Metagenomics characterization of respiratory viral RNA pathogens in children under five years with severe acute respiratory infection in the Free State, South Africa. J Med Virol. 2023 May;95(5): e28753. doi: 10.1002/jmv.28753. PMID: 37212321; PMCID: PMC10952945.
Lanrewaju AA, Enitan-Folami AM, Nyaga MM, Sabiu S, Swalaha FM. Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV-2. J Biomol Struct Dyn. 2024 Aug;42(13):6740-6760. doi: 10.1080/07391102.2023.2236718. Epub 2023 Jul 18. PMID: 37464870.
Lanrewaju AA, Enitan-Folami AM, Nyaga MM, Sabiu S, Swalaha FM. Cheminformatics bioprospection of selected medicinal plants metabolites against trypsin cleaved VP4 (spike protein) of rotavirus A. J Biomol Struct Dyn. 2024;42(20):10652-10671. doi: 10.1080/07391102.2023.2258405. Epub 2023 Sep 20. PMID: 37728550.
Jere KC, Chibwe I, Chaima D, Kasambala W, Mhango C, Bitilinyu-Bangoh J, Mvula B, Kipandula W, Kamng’ona AW, Steele AD, Chauma-Mwale A, Hungerford D, Kagoli M, Nyaga MM, Dube Q, French N, Cunliffe NA, Msefula CL, Chaguza C. Draft genomes of Aeromonas caviae from patients with cholera-like illness during the 2022-2023 cholera outbreak in Malawi. Microbiol Resour Announc. 2023 Oct 19;12(10): e0058023. doi: 10.1128/MRA.00580-23. Epub 2023 Sep 28. PMID: 37768056; PMCID: PMC10586119.
Potgieter RL, Mwangi PN, Mogotsi MT, Uwimana J, Mutesa L, Muganga N, Murenzi D, Tusiyenge L, Seheri ML, Steele AD, Mwenda JM, Nyaga MM. Genomic Analysis of Rwandan G9P [8] Rotavirus Strains Pre- and Post-RotaTeq® Vaccine Reveals Significant Distinct Sub-Clustering in a Post-Vaccination Cohort. Viruses. 2023 Nov 25;15(12):2321. doi: 10.3390/v15122321. PMID: 38140562; PMCID: PMC10747556.
Tegally H, Moir M, Everatt J, Giovanetti M, Scheepers C, Wilkinson E, Subramoney K, Makatini Z, Moyo S, Amoako DG, Baxter C, Althaus CL, Anyaneji UJ, Kekana D, Viana R, Giandhari J, Lessells RJ, Maponga T, Maruapula D, Choga W, Matshaba M, Mbulawa MB, Msomi N; NGS-SA consortium; Naidoo Y, Pillay S, Sanko TJ, San JE, Scott L, Singh L, Magini NA, Smith-Lawrence P, Stevens W, Dor G, Tshiabuila D, Wolter N, Preiser W, Treurnicht FK, Venter M, Chiloane G, McIntyre C, O’Toole A, Ruis C, Peacock TP, Roemer C, Kosakovsky Pond SL, Williamson C, Pybus OG, Bhiman JN, Glass A, Martin DP, Jackson B, Rambaut A, Laguda-Akingba O, Gaseitsiwe S, von Gottberg A, de Oliveira T. Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa. Nat Med. 2022 Sep;28(9):1785-1790. doi: 10.1038/s41591-022-01911-2. Epub 2022 Jun 27. PMID: 35760080; PMCID: PMC9499863.NGS-SA consortium: Armand Phillip Bester, Mathilda Claassen, Deelan Doolabh, Innocent Mudau, Nokuzola Mbhele, Susan Engelbrecht, Dominique Goedhals, Diana Hardie, Nei-Yuan Hsiao, Arash Iranzadeh, Arshad Ismail, Rageema Joseph, Arisha Maharaj, Boitshoko Mahlangu, Kamela Mahlakwane, Ashlyn Davis, Gert Marais, Koleka Mlisana, Anele Mnguni, Thabo Mohale, Gerald Motsatsi, Peter Mwangi, Noxolo Ntuli, Martin Nyaga, Luicer Olubayo, Botshelo Radibe, Yajna Ramphal, Upasana Ramphal, Wilhelmina Strasheim, Naume Tebeila, Stephanie van Wyk, Shannon Wilson, Alexander G Lucaci, Steven Weaver, Akhil Maharaj, Yusasha Pillay, Michaela Davids, Adriano Mendes, Simnikiwe Mayaphi
Tegally H, San JE, Cotten M, Moir M, Tegomoh B, Mboowa G, Martin DP, Baxter C, Lambisia AW, Diallo A, Amoako DG, Diagne MM, Sisay A, Zekri AN, Gueye AS, Sangare AK, Ouedraogo AS, Sow A, Musa AO, Sesay AK, Abias AG, Elzagheid AI, Lagare A, Kemi AS, Abar AE, Johnson AA, Fowotade A, Oluwapelumi AO, Amuri AA, Juru A, Kandeil A, Mostafa A, Rebai A, Sayed A, Kazeem A, Balde A, Christoffels A, Trotter AJ, Campbell A, Keita AK, Kone A, Bouzid A, Souissi A, Agweyu A, Naguib A, Gutierrez AV, Nkeshimana A, Page AJ, Yadouleton A, Vinze A, Happi AN, Chouikha A, Iranzadeh A, Maharaj A, Batchi-Bouyou AL, Ismail A, Sylverken AA, Goba A, Femi A, Sijuwola AE, Marycelin B, Salako BL, Oderinde BS, Bolajoko B, Diarra B, Herring BL, Tsofa B, Lekana-Douki B, Mvula B, Njanpop-Lafourcade BM, Marondera BT, Khaireh BA, Kouriba B, Adu B, Pool B, McInnis B, Brook C, Williamson C, Nduwimana C, Anscombe C, Pratt CB, Scheepers C, Akoua-Koffi CG, Agoti CN, Mapanguy CM, Loucoubar C, Onwuamah CK, Ihekweazu C, Malaka CN, Peyrefitte C, Grace C, Omoruyi CE, Rafaï CD, Morang’a CM, Erameh C, Lule DB, Bridges DJ, Mukadi-Bamuleka D, Park D, Rasmussen DA, Baker D, Nokes DJ, Ssemwanga D, Tshiabuila D, Amuzu DSY, Goedhals D, Grant DS, Omuoyo DO, Maruapula D, Wanjohi DW, Foster-Nyarko E, Lusamaki EK, Simulundu E, Ong’era EM, Ngabana EN, Abworo EO, Otieno E, Shumba E, Barasa E, Ahmed EB, Ahmed EA, Lokilo E, Mukantwari E, Philomena E, Belarbi E, Simon-Loriere E, Anoh EA, Manuel E, Leendertz F, Taweh FM, Wasfi F, Abdelmoula F, Takawira FT, Derrar F, Ajogbasile FV, Treurnicht F, Onikepe F, Ntoumi F, Muyembe FM, Ragomzingba FEZ, Dratibi FA, Iyanu FA, Mbunsu GK, Thilliez G, Kay GL, Akpede GO, van Zyl GU, Awandare GA, Kpeli GS, Schubert G, Maphalala GP, Ranaivoson HC, Omunakwe HE, Onywera H, Abe H, Karray H, Nansumba H, Triki H, Kadjo HAA, Elgahzaly H, Gumbo H, Mathieu H, Kavunga-Membo H, Smeti I, Olawoye IB, Adetifa IMO, Odia I, Ben Boubaker IB, Muhammad IA, Ssewanyana I, Wurie I, Konstantinus IS, Halatoko JWA, Ayei J, Sonoo J, Makangara JC, Tamfum JM, Heraud JM, Shaffer JG, Giandhari J, Musyoki J, Nkurunziza J, Uwanibe JN, Bhiman JN, Yasuda J, Morais J, Kiconco J, Sandi JD, Huddleston J, Odoom JK, Morobe JM, Gyapong JO, Kayiwa JT, Okolie JC, Xavier JS, Gyamfi J, Wamala JF, Bonney JHK, Nyandwi J, Everatt J, Nakaseegu J, Ngoi JM, Namulondo J, Oguzie JU, Andeko JC, Lutwama JJ, Mogga JJH, O’Grady J, Siddle KJ, Victoir K, Adeyemi KT, Tumedi KA, Carvalho KS, Mohammed KS, Dellagi K, Musonda KG, Duedu KO, Fki-Berrajah L, Singh L, Kepler LM, Biscornet L, de Oliveira Martins L, Chabuka L, Olubayo L, Ojok LD, Deng LL, Ochola-Oyier LI, Tyers L, Mine M, Ramuth M, Mastouri M, ElHefnawi M, Mbanne M, Matsheka MI, Kebabonye M, Diop M, Momoh M, Lima Mendonça MDL, Venter M, Paye MF, Faye M, Nyaga MM, Mareka M, Damaris MM, Mburu MW, Mpina MG, Owusu M, Wiley MR, Tatfeng MY, Ayekaba MO, Abouelhoda M, Beloufa MA, Seadawy MG, Khalifa MK, Matobo MM, Kane M, Salou M, Mbulawa MB, Mwenda M, Allam M, Phan MVT, Abid N, Rujeni N, Abuzaid N, Ismael N, Elguindy N, Top NM, Dia N, Mabunda N, Hsiao NY, Silochi NB, Francisco NM, Saasa N, Bbosa N, Murunga N, Gumede N, Wolter N, Sitharam N, Ndodo N, Ajayi NA, Tordo N, Mbhele N, Razanajatovo NH, Iguosadolo N, Mba N, Kingsley OC, Sylvanus O, Femi O, Adewumi OM, Testimony O, Ogunsanya OA, Fakayode O, Ogah OE, Oludayo OE, Faye O, Smith-Lawrence P, Ondoa P, Combe P, Nabisubi P, Semanda P, Oluniyi PE, Arnaldo P, Quashie PK, Okokhere PO, Bejon P, Dussart P, Bester PA, Mbala PK, Kaleebu P, Abechi P, El-Shesheny R, Joseph R, Aziz RK, Essomba RG, Ayivor-Djanie R, Njouom R, Phillips RO, Gorman R, Kingsley RA, Neto Rodrigues RMDESA, Audu RA, Carr RAA, Gargouri S, Masmoudi S, Bootsma S, Sankhe S, Mohamed SI, Femi S, Mhalla S, Hosch S, Kassim SK, Metha S, Trabelsi S, Agwa SH, Mwangi SW, Doumbia S, Makiala-Mandanda S, Aryeetey S, Ahmed SS, Ahmed SM, Elhamoumi S, Moyo S, Lutucuta S, Gaseitsiwe S, Jalloh S, Andriamandimby SF, Oguntope S, Grayo S, Lekana-Douki S, Prosolek S, Ouangraoua S, van Wyk S, Schaffner SF, Kanyerezi S, Ahuka-Mundeke S, Rudder S, Pillay S, Nabadda S, Behillil S, Budiaki SL, van der Werf S, Mashe T, Mohale T, Le-Viet T, Velavan TP, Schindler T, Maponga TG, Bedford T, Anyaneji UJ, Chinedu U, Ramphal U, George UE, Enouf V, Nene V, Gorova V, Roshdy WH, Karim WA, Ampofo WK, Preiser W, Choga WT, Ahmed YA, Ramphal Y, Bediako Y, Naidoo Y, Butera Y, de Laurent ZR; Africa Pathogen Genomics Initiative (Africa PGI)‡; Ouma AEO, von Gottberg A, Githinji G, Moeti M, Tomori O, Sabeti PC, Sall AA, Oyola SO, Tebeje YK, Tessema SK, de Oliveira T, Happi C, Lessells R, Nkengasong J, Wilkinson E. The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. Science. 2022 Oct 7;378(6615):eabq5358. doi: 10.1126/science.abq5358. Epub 2022 Oct 7. PMID: 36108049; PMCID: PMC9529057.
Mwangi PN, Potgieter RL, Simwaka J, Mpabalwani EM, Mwenda JM, Mogotsi MT, Magagula N, Esona MD, Steele AD, Seheri ML, Nyaga MM. Genomic Analysis of G2P[4] Group A Rotaviruses in Zambia Reveals Positive Selection in Amino Acid Site 7 of Viral Protein 3. Viruses. 2023 Feb 11;15(2):501. doi: 10.3390/v15020501. PMID: 36851715; PMCID: PMC9965253.
Ogunbayo AE, Mogotsi MT, Sondlane H, Nkwadipo KR, Sabiu S, Nyaga MM. Metagenomic Analysis of Respiratory RNA Virome of Children with and without Severe Acute Respiratory Infection from the Free State, South Africa during COVID-19 Pandemic Reveals Higher Diversity and Abundance in Summer Compared with Winter Period. Viruses. 2022 Nov 14;14(11):2516. doi: 10.3390/v14112516. PMID: 36423125; PMCID: PMC9692838.
Ogunbayo AE, Mogotsi MT, Sondlane H, Nkwadipo KR, Sabiu S, Nyaga MM. Pathogen Profile of Children Hospitalised with Severe Acute Respiratory Infections during COVID-19 Pandemic in the Free State Province, South Africa. Int J Environ Res Public Health. 2022 Aug 21;19(16):10418. doi: 10.3390/ijerph191610418. PMID: 36012053; PMCID: PMC9408356.
Ogunbayo AE, Sabiu S, Nyaga MM. Evaluation of extraction and enrichment methods for recovery of respiratory RNA viruses in a metagenomics approach. J Virol Methods. 2023 Apr;314:114677. doi: 10.1016/j.jviromet.2023.114677. Epub 2023 Jan 16. PMID: 36657602; PMCID: PMC10009504.
Pambuka GT, Kinge TR, Ghosh S, Cason ED, Nyaga MM, Gryzenhout M. Plant and Soil Core Mycobiomes in a Two-Year Sorghum-Legume Intercropping System of Underutilized Crops in South Africa. Microorganisms. 2022 Oct 20;10(10):2079. doi: 10.3390/microorganisms10102079. PMID: 36296355; PMCID: PMC9611730.
Mwangi PN, Page NA, Seheri ML, Mphahlele MJ, Nadan S, Esona MD, Kumwenda B, Kamng’ona AW, Donato CM, Steele DA, Ndze VN, Dennis FE, Jere KC, Nyaga MM. Evolutionary changes between pre- and post-vaccine South African group A G2P[4] rotavirus strains, 2003-2017. Microb Genom. 2022 Apr;8(4). doi: 10.1099/mgen.0.000809. PMID: 35446251.
Mwangi P, Mogotsi M, Ogunbayo A, Mooko T, Maringa W, Sondlane H, Nkwadipo K, Adelabu O, Bester PA, Goedhals D, Nyaga M. A decontamination strategy for resolving SARS-CoV-2 amplicon contamination in a next-generation sequencing laboratory. Arch Virol. 2022 Mar 17:1–5. doi: 10.1007/s00705-022-05411-z. Epub ahead of print. PMID: 35298714; PMCID: PMC8926888.
Viana R, Moyo S, Amoako DG, Tegally H, Scheepers C, Althaus CL, Anyaneji UJ, Bester PA, Boni MF, Chand M, Choga WT, Colquhoun R, Davids M, Deforche K, Doolabh D, du Plessis L, Engelbrecht S, Everatt J, Giandhari J, Giovanetti M, Hardie D, Hill V, Hsiao NY, Iranzadeh A, Ismail A, Joseph C, Joseph R, Koopile L, Kosakovsky Pond SL, Kraemer MUG, Kuate-Lere L, Laguda-Akingba O, Lesetedi-Mafoko O, Lessells RJ, Lockman S, Lucaci AG, Maharaj A, Mahlangu B, Maponga T, Mahlakwane K, Makatini Z, Marais G, Maruapula D, Masupu K, Matshaba M, Mayaphi S, Mbhele N, Mbulawa MB, Mendes A, Mlisana K, Mnguni A, Mohale T, Moir M, Moruisi K, Mosepele M, Motsatsi G, Motswaledi MS, Mphoyakgosi T, Msomi N, Mwangi PN, Naidoo Y, Ntuli N, Nyaga M, Olubayo L, Pillay S, Radibe B, Ramphal Y, Ramphal U, San JE, Scott L, Shapiro R, Singh L, Smith-Lawrence P, Stevens W, Strydom A, Subramoney K, Tebeila N, Tshiabuila D, Tsui J, van Wyk S, Weaver S, Wibmer CK, Wilkinson E, Wolter N, Zarebski AE, Zuze B, Goedhals D, Preiser W, Treurnicht F, Venter M, Williamson C, Pybus OG, Bhiman J, Glass A, Martin DP, Rambaut A, Gaseitsiwe S, von Gottberg A, de Oliveira T. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa. Nature. 2022 Jan 7. doi: 10.1038/s41586-022-04411-y. Epub ahead of print. PMID: 35042229.
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Manjate F, João ED, Chirinda P, Garrine M, Vubil D, Nobela N, Kotloff K, Nataro JP, Nhampossa T, Acácio S, Tate JE, Parashar U, Mwenda JM, Alonso PL, Nyaga M, Cunha C, Mandomando I. Molecular Epidemiology of Rotavirus Strains in Symptomatic and Asymptomatic Children in Manhiça District, Southern Mozambique 2008-2019. Viruses. 2022 Jan 12;14(1):134. doi: 10.3390/v14010134. PMID: 35062336; PMCID: PMC8781303.
Maringa WM, Simwaka J, Mwangi PN, Mpabalwani EM, Mwenda JM, Mphahlele MJ, Seheri ML, Nyaga MM. Whole Genome Analysis of Human Rotaviruses Reveals Single Gene Reassortant Rotavirus Strains in Zambia. Viruses. 2021 Sep 18;13(9):1872. doi: 10.3390/v13091872. PMID: 34578453; PMCID: PMC8472975.
Rasebotsa S, Uwimana J, Mogotsi MT, Rakau K, Magagula NB, Seheri ML, Mwenda JM, Mphahlele MJ, Sabiu S, Mihigo R, Mutesa L, Nyaga MM. Whole-Genome Analyses Identifies Multiple Reassortant Rotavirus Strains in Rwanda Post-Vaccine Introduction. Viruses. 2021 Jan 12;13(1):E95. doi: 10.3390/v13010095. PMID: 33445703.
Mogotsi MT, Mwangi PN, Bester PA, Mphahlele MJ, Seheri ML, O’Neill HG, Nyaga MM. Metagenomic Analysis of the Enteric RNA Virome of Infants from the Oukasie Clinic, North West Province, South Africa, Reveals Diverse Eukaryotic Viruses. Viruses. 2020 Nov 5;12(11):E1260. doi: 10.3390/v12111260. PMID: 33167516.
Aruwa CE, Pillay C, Nyaga MM, Sabiu S. Poultry gut health – microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies. J Anim Sci Biotechnol. 2021 Dec 2;12(1):119. doi: 10.1186/s40104-021-00640-9. PMID: 34857055; PMCID: PMC8638651.
Pambuka GT, Kinge TR, Ghosh S, Cason ED, Nyaga MM, Gryzenhout M. Baseline Data of the Fungal Phytobiome of Three Sorghum (Sorghum bicolor) Cultivars in South Africa using Targeted Environmental Sequencing. J Fungi (Basel). 2021 Nov 17;7(11):978. doi: 10.3390/jof7110978. PMID: 34829265; PMCID: PMC8622221.
Mwangi PN, Mogotsi MT, Seheri ML, Mphahlele MJ, Peenze I, Esona MD, Kumwenda B, Steele AD, Kirkwood CD, Ndze VN, Dennis FE, Jere KC, Nyaga MM. Whole Genome In-Silico Analysis of South African G1P[8] Rotavirus Strains Before and After Vaccine Introduction Over A Period of 14 Years. Vaccines (Basel). 2020 Oct 14;8(4):E609. doi: 10.3390/vaccines8040609. PMID: 33066615.
Strydom A, Donato CM, Nyaga MM, Boene SS, Peenze I, Mogotsi MT, João ED, Munlela B, Potgieter AC, Seheri ML, de Deus N, O’Neill HG. Genetic Characterisation of South African and Mozambican Bovine Rotaviruses Reveals a Typical Bovine-like Artiodactyl Constellation Derived through Multiple Reassortment Events. Pathogens. 2021 Oct 12;10(10):1308. doi: 10.3390/pathogens10101308. PMID: 34684257; PMCID: PMC8539442.
Maringa WM, Mwangi PN, Simwaka J, Mpabalwani EM, Mwenda JM, Peenze I, Esona MD, Mphahlele MJ, Seheri ML, Nyaga MM. Molecular Characterisation of a Rare Reassortant Porcine-Like G5P[6] Rotavirus Strain Detected in an Unvaccinated Child in Kasama, Zambia. Pathogens. 2020 Aug 17;9(8):663. doi: 10.3390/pathogens9080663.
Mwangi PN, Mogotsi MT, Rasebotsa SP, Seheri ML, Mphahlele MJ, Ndze VN, Dennis FE, Jere KC, Nyaga MM. Uncovering the First Atypical DS-1-like G1P[8] Rotavirus Strains That Circulated during Pre-Rotavirus Vaccine Introduction Era in South Africa. Pathogens. 2020 May 20;9(5):E391. doi: 10.3390/pathogens9050391.Pathogens. 2020.PMID: 32443835.
Rasebotsa S, Mwangi PN, Mogotsi MT, Sabiu S, Magagula NB, Rakau K, Uwimana J, Mutesa L, Muganga N, Murenzi D, Tuyisenge L, Jaimes J, Esona MD, Bowen MD, Mphahlele MJ, Seheri ML, Mwenda JM, Nyaga MM. Whole genome and in-silico analyses of G1P[8] rotavirus strains from pre- and post-vaccination periods in Rwanda. Sci Rep. 2020 Aug 10;10(1):13460. doi: 10.1038/s41598-020-69973-1.PMID: 32778711.
Nyaga MM, Sabiu S, Ndze VN, Dennis FE, Jere KC. Report of the 1st African Enteric Viruses Genome Initiative (AEVGI) Data and Bioinformatics Workshop on Whole-genome Analysis of some African Rotavirus Strains held in Bloemfontein, South Africa. Vaccine 2020 Jul 22;38(34):5402-5407. doi: 10.1016/j.vaccine.2020.06.010. Epub 2020 Jun 17.
Ogundeji AO, Mjokane N, Folorunso OS, Pohl CH, Nyaga MM, Sebolai OM. The Repurposing of Acetylsalicylic Acid as a Photosensitiser to Inactivate the Growth of Cryptococcal Cells. Pharmaceuticals (Basel). 2021 Apr 23;14(5):404. doi: 10.3390/ph14050404. PMID: 33922831.
Rakau KG, Nyaga MM, Gededzha MP, Mwenda JM, Mphahlele MJ, Seheri LM, Steele AD. Genetic characterization of G12P[6] and G12P[8] rotavirus strains collected in six African countries between 2010 and 2014. BMC Infect Dis. 2021 Jan 22;21(1):107. doi: 10.1186/s12879-020-05745-6. PMID: 33482744; PMCID: PMC7821174.
Mokoena F, Seheri ML, Nyaga MM, Magagula N, Mukaratirwa A, Mulindwa A, Abebe A, Boula A, Enyonam T, Rakau K, Peenze I, Mwenda JM, Mphahlele MJ. Whole Genome Analysis of African G12P[6] and G12P[8] Rotaviruses Provides Evidence of Porcine-Human Reassortment at NSP2, NSP3, and NSP4. Front. Microbiol., 12 January 2021 |
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Chaguza C, Nyaga MM, Mwenda JM, Esona MD, Jere KC. Using genomics to improve preparedness and response of future epidemics or pandemics in Africa. Lancet Microbe. 2020 Nov;1(7):e275-e276. doi: 10.1016/S2666-5247(20)30169-5. PMID: 33345202; PMCID:
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Mhango C, Mandolo JJ, Chinyama E, Wachepa R, Kanjerwa O, Malamba-Banda C, Matambo PB, Barnes KG, Chaguza C, Shawa IT, Nyaga MM, Hungerford D, Parashar UD, Pitzer VE, Kamng’ona AW, Iturriza-Gomara M, Cunliffe NA, Jere KC. Rotavirus Genotypes in Hospitalized Children with Acute Gastroenteritis Before and After Rotavirus Vaccine Introduction in Blantyre, Malawi, 1997 – 2019. J Infect Dis. 2020 Oct 9:jiaa616. doi: 10.1093/infdis/jiaa616. Epub ahead of print. PMID: 33033832.
Svardal H, Rusuwa B, Linderoth T, Kiran A, Charmantier A, Lattorff HMG, Cagan A, Ommeh SC, Kamng’ona A, Katongo C, Santos ME, Durbin R, Kumwenda B, Visscher PM, von der Heyden S; participants of SMBE Malawi [Nyaga MM]. Evolutionary genomics at the human-environment interface in Africa. Mol Biol Evol. 2020 May 22:msaa132. doi: 10.1093/molbev/msaa132. Online ahead of print. Mol Biol Evol. 2020.PMID: 32442309.
Strydom A, Motanyane L, Nyaga MM, João ED, Cuamba A, Mandomando I, Cassocera M, de Deus N, O’Neill H. Whole-genome characterization of G12 rotavirus strains detected in Mozambique reveals a co-infection with a GXP[14] strain of possible animal origin. J Gen Virol. 2019 Jun;100(6):932-937. doi: 10.1099/jgv.0.001270. Epub 2019 May 29.J Gen Virol. 2019.PMID: 31140967.
Kinge TR, Cason ED, Valverde A, Nyaga MM, Gryzenhout M. Endophytic seed mycobiome of six sorghum (Sorghum bicolor) cultivars from commercial seedlots using an Illumina sequencing approach. Doi 10.5943/mycosphere/10/1/16. Mycosphere 10 (1): 739–756 (2019) www.mycosphere.org. ISSN 2077 7019.
Strydom A, João ED, Motanyane L, Nyaga MM, Christiaan Potgieter A, Cuamba A, Mandomando I, Cassocera M, de Deus N, O’Neill HG. Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events. Infect Genet Evol. 2019 Apr;69:68-75. doi: 10.1016/j.meegid.2019.01.011. Epub 2019 Jan 11.Infect Genet Evol. 2019.PMID: 30641151.
Nyaga MM, Tan Y, Seheri ML, Halpin RA, Akopov A, Stucker KM, Fedorova NB, Shrivastava S, Duncan Steele A, Mwenda JM, Pickett BE, Das SR, Mphahlele MJ. Whole-genome sequencing and analyses identify high genetic heterogeneity, diversity and endemicity of rotavirus genotype P[6] strains circulating in Africa. Infect Genet Evol. 2018 Sep;63:79-88. doi: 10.1016/j.meegid.2018.05.013. Epub 2018 May 18. Infect Genet Evol. 2018.PMID: 29782933.
Nyaga MM, Peenze I, Potgieter CA, Seheri LM, Page NA, Yinda CK, Steele AD, Matthijnssens J, Mphahlele MJ. Complete genome analyses of the first porcine rotavirus group H identified from a South African pig does not provide evidence for recent interspecies transmission events. Infect Genet Evol. 2016 Mar;38:1-7. doi: 10.1016/j.meegid.2015.11.032. Epub 2015 Nov 30. Infect Genet Evol. 2016.PMID: 26658066.
Mhango, C., Banda, A., Mandolo, J.J., Kumwenda, O., Malamba-Banda, C., Barnes, K.G., Kumwenda, B., Jambo, K., Donato, C.M., Esona, M.D., Mwangi, P.N., Steele A.D., Iturriza-Gomara, M., Donato C.M., Cunliffe, N.A., Ndze, V.N., Kamng’ona A.W., Dennis, F.E., Nyaga, MM, Chaguza, C., Jere, K.C. 2023. Comparative whole genome analysis reveals re-emergence of human Wa-like and DS-1-like G3 rotaviruses after Rotarix vaccine introduction in Malawi. Virus Evolution.
Manjate, F., João, E.D., Mwangi, P., Chirinda, P., Mogotsi, M., Messa Junior, A., Garrine, M., Vubil, D., Nobela, N., Nhampossa, T., Acácio, S., Tate, J.E., Parashar, U., Weldegebriel, G., Mwenda JM, Alonso P.L., Cunha, C., Nyaga, M.M., Mandomando, I. 2023.Genomic characterization of rotavirus G3P [8] strain in vaccinated children, reveals possible reassortment events between human and animal strains in Manhiça District, Mozambique. Frontiers in Microbiology, 14, p.1439.